September 25, 2016

MCQs on Structure of DNA and RNA for Staff Nurse and Medical Exams

1. A peculiar cytochrome is observed in bacteria and it can react with molecular oxygen, what is it?
a. Cyt b
b. Cyt c
c. Cyt d
d. Cyt o

2. The genetic material in HIV is
a. ds DNA
b. ss DNA
c. s RNA
d. None of these

3. Which one of the following mutagens act only on replicating DNA?
a. Ethidium bromide
b. Nitrosogeranidine
c. Acridine orange
d. None of above

4. Poly A tail is frequently found in
a. Histone in RNA
b. Bacterial RNA
c. eukaryotic RNA

5. Which of the following is an example of RNA virus?
a. SV 40
b. T4 phage
c. Tobacco mosaic virus
d. Adeno virus

6. Genomic DNA is extracted, broken into fragments of reasonable size by a restriction endonuclease and then inserted into a cloning vector to generate chimeric vectors. The cloned fragments are called
a. Clones
b. Genomic library
c. mRNA
d. None of these

7. Transgenic animals are produced when GH gene fused with
a. MT gene
b. GH
c. GRF
d. FIX

8. In which medium the hydridoma cells grow selectively?
a. Polyethylene glycol
b. Hypoxanthine aminopterin thyminine
c. Hypoxathing-guaning phosphoribosyl transferase
d. Both b and c

9. The enzymes which are commonly used in genetic engineering are
a. Exonuclease and ligase
b. Restriction endonuclease and polymerase
c. Ligase and polymerase
d. Restriction endonuclease and ligase

10. A successful hybridoma was produced by fusing
a. Plasma cells and plasmids
b. Plasma cells and myeloma cells
c. Myeloma cells and plasmids
d. Plasma cells and bacterial cells

11. The technique involved in comparing the DNA components of two samples is known as
a. Monoclonal antibody techniques
b. Genetic finger printing
c. Recombinant DNA technology
d. Polymerase chain reaction

12. Plasmids are ideal vectors for genecloning as
a. They can be multiplied by culturing
b. They can be multiplied in the laboratory using enzymes
c. They can replicate freely outside the bacterial cell
d. They are self replicating within the bacterial cell

13. Humans normally have 46 chromosomes in skin cells. How many autosomes would be expected in a kidney cell?
a. 46
b. 23
c. 47
d. 44

14. Pasteur effect is due to
a. Change from aerobic to anaerobic
b. Providing oxygen to anaerobically respiring structures
c. Rapid utilization of ATP
d. Nonsynthesis of ATP

15. A mechanism that can cause a gene to move from one linkage group to another is
a. Trans location
b. Inversion
c. Crossing over
d. Duplication

16. The smallest unit of genetic material that can undergo mutation is called
a. Gene
b. Cistron
c. Replicon
d. Muton

17. The two chromatids of metaphase chrosome represent
a. Replicated chromosomes to be separated at anaphase
b. Homologous chromosomes of a diploid set
c. Non-homologous chromosomes joined at the centromere
d. Maternal and paternal chromosomes joined at the centromere

18. Malate dehydrogenase enzyme is a
a. Transferase
b. Hydrolase
c. Isomerase
d. Oxido reductase

19. In E.Coli att site is in between
a. Gal and biogenes
b. Bio and niacin genes
c. Gal and B genes
d. None of these

20. The best vector for gene cloning
a. Relaxed control plasmid
b. Stringent control plasmid
c. Both a and b
d. None of these

21. A gene that takes part in the synthesis of polypeptide is
a. Structural gene
b. Regulator gene
c. Operator gene
d. Promoter gene

22. DNA replicates during
a. G1 – phase
b. S – phase
c. G2 – phase
d. M – phase

23. A human cell containing 22 autosome and a ‘Y’ chromosome is probably a
a. Male somatic cell
b. Zygote
c. Female somatic cell
d. Sperm cell

24. Crossing-over most commonly occurs during
a. Prophase I
b. Prophase II
c. Anaphase I
d. Telophase II

25. DNA-replication is by the mechanism of
a. Conservative
b. Semiconservative
c. Dispersive
d. None of the above

26. Production of RNA from DNA is called
a. Translation
b. RNA splicing
c. Transcription
d. Transposition

27. Nucleic acids contain
a. Alanine
b. Adenine
c. Lysine
d. Arginine

28. What are the structural units of nucleic acids?
a. N-bases
b. Nucleosides
c. Nucleotides
d. Histones

29. The most important function of a gene is to synthesize
a. Enzymes
b. Hormones
c. RNA
d. DNA

30. One of the genes present exclusively on the X-chromosome in humans is concerned with
a. Baldness
b. Red-green colour baldness
c. Facial hair/moustache in males
d. Night blindness

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MCQs on Structure of DNA and RNA for Staff Nurse and Medical Exams Reviewed by Rohit Ranjan on Sunday, September 25, 2016 Rating: 5 1. A peculiar cytochrome is observed in bacteria and it can react with molecular oxygen, what is it? a. Cyt b b. Cyt c c. Cyt d d. C...